The Bio-Response High Temperature Continuous Batch EDS has become the industry standard for quality, technology, and reliablity for your BSL-3 or BSL-4 facility. This system operates at a user adjustable 250 - 305 degrees F (121 - 152 degrees C) depending on the types of microorganisms present in the lab. The High Temperature EDS is available in many redundant and non-redundant configurations to meet the space and processing needs of your facility.

 

 

 

High Temperature Continuous Batch Pros/Cons
Advantages (Pros)	Operates at 121°C / 250°F or higher for thermal sterilization
	Sterilization without question regardless of solids situation
	Easy to validate
	Parametric monitoring acceptable
	Shorter Cook Cycle
	Can be heated by electric immersion coils or steam coil
	Can be heated by live steam
	Fully ethernet integrated controls are a standard feature
	Suitable for all biosafety levels (1-4)
	Integral strainer basket standard for solids sterilization
	One collector, two cooker systems can be fitted with an 85% energy recovery skid
Disadvantages (Cons)	Higher cost system
	Highest cost of operation (requires more energy to heat, more energy to cool)
	Requires operation at pressure in a pressure vessel
General Discussion	This is the gold standard for Effluent Decontamination Systems. It is the "wet heat sterilizer" regardless of solids content or organic conditions of the waste. Systems must feature (due to pressurized operation) an array of special design features to prevent problems (double inlet valves, power flush primary inlet valve, double discharge valves, etc.) so maintenance requirements are industry-standard very low, but are greater than the lower temperature or chemical only systems.

 

 

 

Approximate time required to inactivate microorganisms by thermal treatment*
Microorgamism	200 degrees F 93 degrees C	212 degrees F 100 degrees C	250 degrees F 121 degrees C
Geobacillus stearothermophilus	> 10 hours	~ 10 hours	< 15 min
Bacillus atrophaeus	< 45 min	< 30 min	< 1 min
Bacillus anthracis	< 45 min	< 30 min	< 1 min
All vegetative bacterial, fungal, and viral pathogens	< 15 min	< 10 min	< 30 seconds
*Assumes wet heat, as exists in an EDS cooker (dry heat requires dramatically longer times). *10 log 6 reduction is the standard of reduction for this chart.
The highlighted green section indicates the thermal operating parameters of the Bio-Response High Temperature EDS.

 

 

 

Bio-Response Unique Features
Feature	Benefit
Liquiphant Piezoelectric Level Sensors	Redundant Liquiphant level sensors eliminate troublesome load cells, unsafe associated flexible drain connection lines, and unreliable radar or sonar level sensing devices.
Internal Heating Coils	Faster heating and drastically increases vessel life.
Welded Stainless Steel Skins	Insulation is completely sealed and safe. We have the safest, most attractive, and highest quality vessels in the EDS industry.
Internal Solids Basket	Collects and treats solids so that you never have a safety hazzard or drain problems.
Dual Inlet Ball Valves	Our dual ball valves with flush system ensures isolation with no leaks and long valve life. All of our valves are rated at over 1 million cycles.
Dual Drain Ball Valves	Our dual ball valves with air test ensure drain isolation with no leaks and long valve life. All of our valves are rated at over 1 million cycles.
Easy Access Man-Way	Our man-way is easily opened and handles by one person and features a double o-ring seal with air test. If this air test fails, and alarm is generated and the machine will not run.
Quiet Sparger	Bio-Response is known for energy and water conservation.  The quiet sparger is an example of this commitment put into action.  Cool with less water and save energy. The quiet sparger to discharge has no pump, no moving parts, uses less cooling water, and only cools the effluent.  The heat in the vessel is retained for the next cycle
Pop-Offs the right way	No expensive pressure vessel required! We build our pop-off systems to ASME code.
No short stubs	Our short, large diameter stubs leave allow sterilization temperatures to reach mounted devices.  There are no cold spots; safe and complete processing occurs in a Bio-Response EDS every cycle.
GE Fanuc Controls	State-of-the-art touch screen with Ethernet connectivity. This is the most technologically advanced and versatile system available and it is standard on all Bio-Response systems.

 

 

Non-Redundant
	Two high temperature cookers
	One collection tank and one cooker (collection tank may be pre-heated)
Redundant
	Three or more high temperature cookers
	One collection tank and two cookers (collection tank may be pre-heated)